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Literature summary for 1.14.19.70 extracted from

  • Duffell, K.M.; Hudson, S.A.; McLean, K.J.; Munro, A.W.; Abell, C.; Matak-Vinkovic, D.
    Nanoelectrospray ionization mass spectrometric study of Mycobacterium tuberculosis CYP121-ligand interactions (2013), Anal. Chem., 85, 5707-5714.
    View publication on PubMed
Search for more literature for 1.14.19.70

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
44962
-
 2 * 44962, calculated from amino acid sequence, CYP121 is a predominantly dimeric protein, with a minor monomeric form present Mycobacterium tuberculosis
89940
-
 nanoelectrospray ionization mass spectrometry Mycobacterium tuberculosis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cyclo(L-tyrosyl-L-tyrosyl) + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2 Mycobacterium tuberculosis
-
 mycocyclosin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O
-
 ?
cyclo(L-tyrosyl-L-tyrosyl) + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2 Mycobacterium tuberculosis H37Rv
-
 mycocyclosin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Mycobacterium tuberculosis P9WPP7
-
-
Mycobacterium tuberculosis H37Rv P9WPP7
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cyclo(L-tyrosyl-L-tyrosyl) + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2
-
 Mycobacterium tuberculosis mycocyclosin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O
-
 ?
cyclo(L-tyrosyl-L-tyrosyl) + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2
-
 Mycobacterium tuberculosis H37Rv mycocyclosin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O
-
 ?

Subunits

Subunits Comment Organism
homodimer 2 * 44962, calculated from amino acid sequence, CYP121 is a predominantly dimeric protein, with a minor monomeric form present Mycobacterium tuberculosis

Synonyms

Synonyms Comment Organism
CYP121
-
 Mycobacterium tuberculosis

General Information

General Information Comment Organism
physiological function the enzyme is essential for bacterial viability Mycobacterium tuberculosis