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Literature summary for 1.14.20.6 extracted from

  • Mahajan, M.; Ahuja, P.S.; Yadav, S.K.
    Post-transcriptional silencing of flavonol synthase mRNA in tobacco leads to fruits with arrested seed set (2011), PLoS ONE, 6, e28315.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.14.20.6

Protein Variants

Protein Variants Comment Organism
additional information silencing of FLS gene by RNAi, in lines G12, A2, B1 and E13, the quercetin content is increased by 351%, 49%, 157% and 258%, the silenced lines show arrest in pollen tube germination, and the pollen tubes grows only to about nine-tenths of the way down the style, and tube tips are swollen, contents of anthocyanins, epigallocatechin, and epicatechin are altered and content in indole acetic acid is reduced compared to the wild-type, overview Nicotiana tabacum
additional information silencing of FLS1 gene by RNAi, in lines G12, A2, B1 and E13, the quercetin content is increased by 351%, 49%, 157% and 258%, the silenced lines show arrest in pollen tube germination, and the pollen tubes grows only to about nine-tenths of the way down the style, and tube tips are swollen, contents of anthocyanins, epigallocatechin, and epicatechin are altered and content in indole acetic acid is reduced compared to the wild-type, overview Nicotiana tabacum

Metals/Ions

Metals/Ions Comment Organism Structure
Fe2+ required Nicotiana tabacum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(2R/3R)-dihydroquercetin + 2-oxoglutarate + O2 Nicotiana tabacum
-
 quercetin + succinate + CO2 + H2O
-
 ?
a dihydroflavonol + 2-oxoglutarate + O2 Nicotiana tabacum
-
 a flavonol + succinate + CO2 + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Nicotiana tabacum A9ZMJ0 FLS; cv. Xanthi
-
Nicotiana tabacum Q1PHN5 FLS1; cv. Xanthi
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(2R/3R)-dihydroquercetin + 2-oxoglutarate + O2
-
 Nicotiana tabacum quercetin + succinate + CO2 + H2O
-
 ?
a dihydroflavonol + 2-oxoglutarate + O2
-
 Nicotiana tabacum a flavonol + succinate + CO2 + H2O
-
 ?

Synonyms

Synonyms Comment Organism
FLS
-
 Nicotiana tabacum
FLS1
-
 Nicotiana tabacum

General Information

General Information Comment Organism
malfunction post-transcriptional silencing of flavonol synthase mRNA in tobacco leads to fruits with arrested seed set, FLS silenced lines show 20-80% reduction in FLS encoding gene expression and 25-93% reduction in quercetin content, as well as a reduction in anthocyanidins content. Content of flavan-3-ols, i.e. catechin, epi-catechin and epigallocatechin, is increased in the transgenic lines, phenotypes, overview Nicotiana tabacum
malfunction post-transcriptional silencing of flavonol synthase mRNA in tobacco leads to fruits with arrested seed set, FLS1 silenced lines show 20-80% reduction in FLS1 encoding gene expression and 25-93% reduction in quercetin content, as well as a reduction in anthocyanidins content. Content of flavan-3-ols, i.e. catechin, epi-catechin and epigallocatechin, is increased in the transgenic lines, phenotypes, overview Nicotiana tabacum
metabolism the FLS enzyme competes with dihydroflavonol 4-reductase for the common substrate dihydroflavonols Nicotiana tabacum