Literature summary for 1.14.99.29 extracted from

Frey, A.G.; Nandal, A.; Park, J.H.; Smith, P.M.; Yabe, T.; Ryu, M.S.; Ghosh, M.C.; Lee, J.; Rouault, T.A.; Park, M.H.; Philpott, C.C.
Iron chaperones PCBP1 and PCBP2 mediate the metallation of the dinuclear iron enzyme deoxyhypusine hydroxylase (2014), Proc. Natl. Acad. Sci. USA, 111, 8031-8036 .

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Metals/Ions

Metals/Ions	Comment	Organism	Structure
Iron	dinuclear iron enzyme	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
[eIF5A]-deoxyhypusine + AH2 + O2	Homo sapiens	-	[eIF5A]-hypusine + A + H2O	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q9BU89	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
HEK-293T cell	-	Homo sapiens	-
Huh-7 cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
[eIF5A]-deoxyhypusine + AH2 + O2	-	Homo sapiens	[eIF5A]-hypusine + A + H2O	-	?

Subunits

Subunits	Comment	Organism
?	x * 39000, FLAG-tagged enzyme, SDS-PAGE	Homo sapiens

Synonyms

Synonyms	Comment	Organism
deoxyhypusine hydroxylase	-	Homo sapiens
DOHH	-	Homo sapiens

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Release 2023.1 (January 2023)