Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
cholesterol + AH2 + O2 | Homo sapiens | - |
25-hydroxycholesterol + A + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q95992 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hepatocyte | - |
Homo sapiens | - |
hepatoma cell | - |
Homo sapiens | - |
liver | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cholesterol + AH2 + O2 | - |
Homo sapiens | 25-hydroxycholesterol + A + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CH25H | - |
Homo sapiens |
cholesterol-25-hydroxylase | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | the enzyme expression in primary human hepatocytes is primarily and transiently induced by type I interferon. Infection with hepatitis C virus causes up-regulation of the enzyme in vivo | up |
General Information | Comment | Organism |
---|---|---|
physiological function | enzyme expression in human hepatoma cells restricts hepatitis C virus infection in a genotype-independent manner | Homo sapiens |