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Literature summary for 1.14.99.44 extracted from

  • Mijts, B.N.; Lee, P.C.; Schmidt-Dannert, C.
    Identification of a carotenoid oxygenase synthesizing acyclic xanthophylls: combinatorial biosynthesis and directed evolution (2005), Chem. Biol., 12, 453-460.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli JM109 cells Staphylococcus aureus

Organism

Organism UniProt Comment Textmining
Staphylococcus aureus Q8NUQ6
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2,4,2',4'-tetradehydrolycopene + AH2 + O2
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Staphylococcus aureus 2,4,2',4'-tetradehydrolycopendial + A + H2O
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?
4,4'-diapolycopene + AH2 + O2
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Staphylococcus aureus 4,4'-diapolycopen-4,4'-dial + A + H2O
-
?
additional information CrtOx catalyses both the oxidation of C30 carotenoids to aldehydes and the further oxidation of these aldehyde groups to carboxylic acids Staphylococcus aureus ?
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?
additional information very low carotenoid yields are observed when CrtOx is complemented with the C40 carotenoid lycopene pathway Staphylococcus aureus ?
-
?

Synonyms

Synonyms Comment Organism
CrtOx
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Staphylococcus aureus