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Literature summary for 1.14.99.68 extracted from

  • Park, K.; Li, N.; Kwak, Y.; Srnec, M.; Bell, C.B.; Liu, L.V.; Wong, S.D.; Yoda, Y.; Kitao, S.; Seto, M.; Hu, M.; Zhao, J.; Krebs, C.; Bollinger, J.M.; Solomon, E.I.
    Peroxide activation for electrophilic reactivity by the binuclear non-heme iron enzyme AurF (2017), J. Am. Chem. Soc., 139, 7062-7070 .
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Streptomyces thioluteus Q70KH9
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-aminobenzoate + reduced acceptor + 2 O2
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 Streptomyces thioluteus 4-nitrobenzoate + acceptor + 2 H2O
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General Information

General Information Comment Organism
physiological function reduced AurF's electronic and geometric structures are poised to react rapidly with O2. The active peroxo intermediate has a protonated peroxo bridge. The protonation activates peroxide for electrophilic/single-electron-transfer reactivity Streptomyces thioluteus