Literature summary for 1.15.1.1 extracted from

Henry, L.E.A.; Cammack, R.; Schwitzguebel, J.P.; Palmer, J.M.; Hall, D.O.
Intracellular localization, isolation and characterization of two distinct varieties of superoxide dismutase from Neurospora crassa (1980), Biochem. J., 187, 321-328.

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Inhibitors

Inhibitors	Comment	Organism	Structure
CN-	contains a cyanide-sensitive enzyme in cytosol and mitochondrial intermembrane space and one cyanide-insensitive enzyme in mitochondrial matrix; Cu,Zn-SOD; no inhibition Mn-SOD	Neurospora crassa
N3-	no inhibition: Zn,Cu-SOD	Neurospora crassa

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytoplasm	-	Neurospora crassa	5737	-
mitochondrion	Mn-SOD	Neurospora crassa	5739	-

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Cu2+	mitochondrial cyanide-sensitive enzyme	Neurospora crassa
Zn2+	mitochondrial cyanide-sensitive enzyme	Neurospora crassa
Zn2+	2 mol of Zn2+ per mol of enzyme	Neurospora crassa

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
30800	31600	mitochondrial cyanide-sensitive enzyme, gel filtration, sedimentation equilibrium analysis	Neurospora crassa
31000	-	about, Cu,Zn-SOD and Mn-SOD, gel filtration	Neurospora crassa

Organism

Organism	UniProt	Comment	Textmining
Neurospora crassa	-	Cu,Zn-SOD	-
Neurospora crassa	-	Mn-SOD	-
Neurospora crassa CuZn-SOD	-	Cu,Zn-SOD	-
Neurospora crassa Mn-SOD	-	Mn-SOD	-

Purification (Commentary)

Purification (Comment)	Organism
Cu, Zn-SOD and Mn-SOD	Neurospora crassa

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
additional information	-	-	Neurospora crassa

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
O2- + H+	-	Neurospora crassa	O2 + H2O2	-	?
O2- + H+	-	Neurospora crassa CuZn-SOD	O2 + H2O2	-	?
O2- + H+	-	Neurospora crassa Mn-SOD	O2 + H2O2	-	?

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Release 2023.1 (January 2023)