Literature summary for 1.15.1.1 extracted from

Abreu, I.A.; Saraiva, L.M.; Soares, C.M.; Teixeira, M.; Cabelli, D.E.
The mechanism of superoxide scavenging by Archaeoglobus fulgidus neelaredoxin (2001), J. Biol. Chem., 276, 38995-39001.

Search for more literature for 1.15.1.1

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichi coli	Archaeoglobus fulgidus

Protein Variants

Protein Variants	Comment	Organism
E12Q	superoxide dismutase activity shows a 29% increase in activity relative to activity of the wild-type enzyme	Archaeoglobus fulgidus
E12V	superoxide dismutase activity shows a 47% increase in activity relative to activity of the wild-type enzyme	Archaeoglobus fulgidus

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Iron	the enzyme is a tetramer with 4 iron centers, one iron per monomer	Archaeoglobus fulgidus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2 superoxide + 2 H+	Archaeoglobus fulgidus	detoxification of superoxide	O2 + H2O2	-	?

Organism

Organism	UniProt	Comment	Textmining
Archaeoglobus fulgidus	O29903	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Archaeoglobus fulgidus

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2 superoxide + 2 H+	-	Archaeoglobus fulgidus	O2 + H2O2	-	?
2 superoxide + 2 H+	detoxification of superoxide	Archaeoglobus fulgidus	O2 + H2O2	-	?

Subunits

Subunits	Comment	Organism
tetramer	-	Archaeoglobus fulgidus

Synonyms

Synonyms	Comment	Organism
neelaredoxin	-	Archaeoglobus fulgidus
Nlr	-	Archaeoglobus fulgidus
SOD	-	Archaeoglobus fulgidus

General Information

General Information	Comment	Organism
physiological function	detoxification of superoxide	Archaeoglobus fulgidus

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Release 2023.1 (January 2023)