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Literature summary for 1.17.1.4 extracted from

  • Fhaolain, I.N.; Coughlan, M.P.
    Effects of limited proteolysis on the structure and activity of turkey liver xanthine dehydrogenase (1977), Biochem. Soc. Trans., 5, 1705-1707.
    View publication on PubMed

Metals/Ions

Metals/Ions Comment Organism Structure
Fe iron-sulfur groups Meleagris gallopavo
Mo
-
Meleagris gallopavo

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
hypoxanthine + NAD+ + H+ + O2- + H2O Meleagris gallopavo subtilisin treatment leads to an active component I of 120000 kDa xanthine + NADH + H2O2
-
?
xanthine + NAD+ + H2O Meleagris gallopavo subtilisin treatment leads to an active component I of 120000 kDa urate + NADH
-
?
xanthine + O2 + H2O Meleagris gallopavo subtilisin treatment leads to an active component I of 120000 kDa urate + O2- + 2 H+
-
?

Organism

Organism UniProt Comment Textmining
Meleagris gallopavo
-
turkey
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Meleagris gallopavo
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
hypoxanthine + NAD+ + H+ + O2- + H2O subtilisin treatment leads to an active component I of 120000 kDa Meleagris gallopavo xanthine + NADH + H2O2
-
?
NADH + electron acceptor + H2O subtilisin treatment leads to an active component of 120000 kDa with enhanced activity Meleagris gallopavo NAD+ + reduced electron acceptor
-
?
NADH + electron acceptor + H2O NADH diaphorase activity with several acceptors Meleagris gallopavo NAD+ + reduced electron acceptor
-
?
xanthine + 2,6-dichlorophenolindophenol + H2O subtilisin treatment leads to an active component of 120000 kDa Meleagris gallopavo urate + ?
-
?
xanthine + methylene blue + H2O subtilisin treatment leads to an active component of 120000 kDa Meleagris gallopavo urate + reduced methylene blue
-
?
xanthine + NAD+ + H2O subtilisin treatment leads to an active component I of 120000 kDa Meleagris gallopavo urate + NADH
-
?
xanthine + O2 + H2O subtilisin treatment leads to an active component I of 120000 kDa Meleagris gallopavo urate + O2- + 2 H+
-
?
xanthine + trinitrobenzenesulfonate + H2O subtilisin treatment leads to an active component of 120000 kDa Meleagris gallopavo urate + ?
-
?

pH Stability

pH Stability pH Stability Maximum Comment Organism
11
-
no effect on activity Meleagris gallopavo

Cofactor

Cofactor Comment Organism Structure
FAD
-
Meleagris gallopavo
NAD+
-
Meleagris gallopavo