Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.17.1.4 extracted from

  • Kaminski, Z.W.; Jezewska, M.M.
    Effect of NADH on hypoxanthine hydroxylation by native NAD+-dependent xanthine oxidoreductase of rat liver, and the possible biological role of this effect (1981), Biochem. J., 200, 597-603.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.17.1.4

Inhibitors

Inhibitors Comment Organism Structure
NADH accumulation of produced NADH inhibits activity to 50% Rattus sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
hypoxanthine + NAD+ + H+ + O2- + H2O Rattus sp.
-
 xanthine + NADH + H2O2
-
 ?
xanthine + NAD+ + H2O Rattus sp.
-
 urate + NADH
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus sp.
-
-
-

Purification (Commentary)

Purification (Comment) Organism
to homogeneity, affinity chromatography Rattus sp.

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus sp.
-

Storage Stability

Storage Stability Organism
-20°C, pH 8.6, 3 days Rattus sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
hypoxanthine + NAD+ + H+ + O2- + H2O
-
 Rattus sp. xanthine + NADH + H2O2
-
 ?
xanthine + NAD+ + H2O
-
 Rattus sp. urate + NADH
-
 ?

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Rattus sp.