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Literature summary for 1.17.1.4 extracted from

  • Hesberg, C.; Hansch, R.; Mendel, R.R.; Bittner, F.
    Tandem orientation of duplicated xanthine dehydrogenase genes from Arabidopsis thaliana: differential gene expression and enzyme activities (2004), J. Biol. Chem., 279, 13547-13554.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
-
Arabidopsis thaliana

Inhibitors

Inhibitors Comment Organism Structure
allopurinol strong Arabidopsis thaliana
p-hydroxymercuribenzoate strong Arabidopsis thaliana
potassium cyanide strong Arabidopsis thaliana

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
150000
-
2 * 150000, SDS-PAGE Arabidopsis thaliana
270000 300000 gel filtration Arabidopsis thaliana

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q8GUQ8 isozyme XDH1, expression in Pichia pastoris
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf cold stress causes decrease, desiccation and senesence cause strong increase in activity Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-naphthaldehyde + NAD+ + ? 27.5% of the activity with xanthine Arabidopsis thaliana ? + NADH
-
?
abscisic aldehyde + NAD+ + ? 28.9% of the activity with xanthine Arabidopsis thaliana ? + NADH
-
?
heptaldehyde + NAD+ + ? 12.5% of the activity with xanthine Arabidopsis thaliana ? + NADH
-
?
hypoxanthine + NAD+ + H+ + O2- + H2O 94.7% of the activity with xanthine Arabidopsis thaliana xanthine + NADH + H2O2
-
?
indole-3-carboxaldehyde + NAD+ + ? 31.3% of the activity with xanthine Arabidopsis thaliana ? + NADH
-
?
purine + NAD+ + ? 10.3% of the activity with xanthine Arabidopsis thaliana ? + NADH
-
?
xanthine + NAD+ + H2O
-
Arabidopsis thaliana urate + NADH
-
?

Subunits

Subunits Comment Organism
dimer 2 * 150000, SDS-PAGE Arabidopsis thaliana

pH Range

pH Minimum pH Maximum Comment Organism
8 8.5
-
Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Arabidopsis thaliana