Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ADP | competitive inhibition of CDP reduction | Herpes simplex virus | |
ATP | free ATP, 0.32 mM, 50% inhibition | Herpes simplex virus | |
CDP | competitive inhibition of ADP reduction | Herpes simplex virus | |
Mg2+ | uncomplexed Mg2+, 3.7 mM, 50% inhibition | Herpes simplex virus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00049 | - |
CDP | - |
Herpes simplex virus | |
0.0078 | - |
ADP | - |
Herpes simplex virus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Herpes simplex virus | - |
type 2, HSV-2 | - |
Purification (Comment) | Organism |
---|---|
HSV type 2 | Herpes simplex virus |
Source Tissue | Comment | Organism | Textmining |
---|
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
4.3 | - |
Herpes simplex virus type 2 enzyme, CDP reduction | Herpes simplex virus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ADP + thioredoxin | - |
Herpes simplex virus | 2'-dADP + thioredoxin disulfide + H2O | - |
r | |
CDP + thioredoxin | - |
Herpes simplex virus | 2'-dCDP + thioredoxin disulfide + H2O | - |
r | |
ribonucleoside diphosphate + reduced thioredoxin | - |
Herpes simplex virus | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
ir |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00042 | - |
CDP | competitive inhibition of ADP reduction | Herpes simplex virus | |
0.011 | - |
ADP | competitive inhibition of CDP reduction | Herpes simplex virus |