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Literature summary for 1.17.4.4 extracted from
- Purification and properties of a factor from rat liver cytosol which stimulates vitamin K epoxide reductase (1983), Arch. Biochem. Biophys., 223, 129-139.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| Protein factor | activation, two different protein factors from rat liver cytosol | Rattus norvegicus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| warfarin | i.e. 3-(alpha-acetonylbenzyl)-4-hydroxycoumarin, inhibition decreased by DTT | Rattus norvegicus |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | integral membrane protein | Rattus norvegicus | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
Holtzman strain | - |
| Rattus norvegicus Holtzman | - |
Holtzman strain | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| vitamin K 2,3-epoxide + dithiothreitol | - |
Rattus norvegicus | vitamin K + oxidized dithiothreitol | - |
? | |
| vitamin K 2,3-epoxide + dithiothreitol | - |
Rattus norvegicus Holtzman | vitamin K + oxidized dithiothreitol | - |
? | |
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Release 2023.1 (January 2023)
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