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Literature summary for 1.17.4.4 extracted from
- VKORC1: a warfarin-sensitive enzyme in vitamin K metabolism and biosynthesis of vitamin K-dependent blood coagulation factors (2008), Vitam. Horm., 78, 227-246.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in HEK-293 cells | Homo sapiens |
| expressed in HEK-293 cells | Rattus norvegicus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| calumenin | - |
Homo sapiens | |
| calumenin | - |
Rattus norvegicus | |
| dicoumarol | - |
Rattus norvegicus |  |
| dicumarol | - |
Homo sapiens | |
| warfarin | - |
Homo sapiens | |
| warfarin | - |
Rattus norvegicus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| vitamin K 2,3-epoxide + dithiothreitol | - |
Homo sapiens | vitamin K + oxidized dithiothreitol | - |
? | |
| vitamin K 2,3-epoxide + dithiothreitol | - |
Rattus norvegicus | vitamin K + oxidized dithiothreitol | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| vitamin K epoxide reductase complex subunit 1 | - |
Homo sapiens |
| vitamin K epoxide reductase complex subunit 1 | - |
Rattus norvegicus |
| vitamin K-2,3-epoxide reductase | - |
Homo sapiens |
| vitamin K-2,3-epoxide reductase | - |
Rattus norvegicus |
| VKOR | - |
Homo sapiens |
| VKOR | - |
Rattus norvegicus |
| VKORC1 | - |
Homo sapiens |
| VKORC1 | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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