Literature summary for 1.17.4.4 extracted from

Krettler, C.; Bevans, C.G.; Reinhart, C.; Watzka, M.; Oldenburg, J.
Tris(3-hydroxypropyl)phosphine is superior to dithiothreitol for in vitro assessment of vitamin K 2,3-epoxide reductase activity (2015), Anal. Biochem., 474, 89-94 .

Search for more literature for 1.17.4.4

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Pichia pastoris	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q9BQB6	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2,3-epoxy-2-methyl-3-phytyl-2,3-dihydro-1,4-naphthoquinone + tris(3-hydroxypropyl)phosphine	by replacing dithiothreitol with tris(3-hydroxypropyl)phosphine and replacing imidazole with phosphate as pH buffer, all nonenzymatic side reactions are effectively eliminated and accurate measurement of enzymatic activity in vitro is possible	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
vitamin K 2,3-epoxide reductase	-	Homo sapiens
VKOR	-	Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
25	-	assay at	Homo sapiens

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
7.4	-	assay at	Homo sapiens

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Release 2023.1 (January 2023)