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Literature summary for 1.17.4.4 extracted from

  • Tew, B.Y.; Hong, T.B.; Otto-Duessel, M.; Elix, C.; Castro, E.; He, M.; Wu, X.; Pal, S.K.; Kalkum, M.; Jones, J.O.
    Vitamin K epoxide reductase regulation of androgen receptor activity (2017), Oncotarget, 8, 13818-13831 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.17.4.4

Inhibitors

Inhibitors Comment Organism Structure
warfarin warfarin inhibits androgen receptor activity (an important driver of prostate cancer development and progression) by inhibiting vitamin K epoxide reductase Homo sapiens
warfarin warfarin inhibits androgen receptor activity (an important driver of prostate cancer development and progression) by inhibiting vitamin K epoxide reductase Mus musculus

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9BQB6 vitamin K epoxide reductase complex subunit 1
-
Mus musculus Q9CRC0
-
-

Source Tissue

Source Tissue Comment Organism Textmining
epithelial cell
-
 Mus musculus
-
prostate epithelium cell line
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
vitamin K epoxide reductase
-
 Homo sapiens
vitamin K epoxide reductase
-
 Mus musculus
VKOR
-
 Homo sapiens
VKOR
-
 Mus musculus

General Information

General Information Comment Organism
metabolism a key enzyme in the vitamin K cycle Homo sapiens
metabolism a key enzyme in the vitamin K cycle Mus musculus