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Literature summary for 1.17.98.4 extracted from

  • Robinson, W.E.; Bassegoda, A.; Reisner, E.; Hirst, J.
    Oxidation-state-dependent binding properties of the active site in a Mo-containing formate dehydrogenase (2017), J. Am. Chem. Soc., 139, 9927-9936 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.17.98.4

Inhibitors

Inhibitors Comment Organism Structure
N3- formate oxidation is inhibited strongly and competitively whereas CO2 reduction is inhibited weakly and not competitively; strongly inhibits the oxidation of formate, whereas CO2 reduction is inhibited only weakly and not competitively Escherichia coli
NO2- formate oxidation is inhibited strongly and competitively whereas CO2 reduction is inhibited weakly and not competitively; strongly inhibits the oxidation of formate, whereas CO2 reduction is inhibited only weakly and not competitively Escherichia coli
NO3- formate oxidation is inhibited strongly and competitively whereas CO2 reduction is inhibited weakly and not competitively; strongly inhibits the oxidation of formate, whereas CO2 reduction is inhibited only weakly and not competitively Escherichia coli
OCN- formate oxidation is inhibited strongly and competitively whereas CO2 reduction is inhibited weakly and not competitively; strongly inhibits the oxidation of formate, whereas CO2 reduction is inhibited only weakly and not competitively Escherichia coli
SCN- formate oxidation is inhibited strongly and competitively whereas CO2 reduction is inhibited weakly and not competitively; strongly inhibits the oxidation of formate, whereas CO2 reduction is inhibited only weakly and not competitively Escherichia coli

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.8
-
 formate pH and temperature not specified in the publication Escherichia coli
2.5
-
 CO2 pH and temperature not specified in the publication Escherichia coli

Metals/Ions

Metals/Ions Comment Organism Structure
Molybdenum contains molybdenum Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Escherichia coli P07658
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CO2 + reduced benzyl viologen
-
 Escherichia coli formate + benzyl viologen
-
 r
formate + acceptor
-
 Escherichia coli CO2 + reduced acceptor
-
 ?
formate + benzyl viologen
-
 Escherichia coli CO2 + reduced benzyl viologen
-
 r

Synonyms

Synonyms Comment Organism
Fdh-H
-
 Escherichia coli
formate dehydrogenase H
-
 Escherichia coli
molybdenum-containing formate dehydrogenase H
-
 Escherichia coli

Cofactor

Cofactor Comment Organism Structure
molybdenum cofactor
-
 Escherichia coli