Literature summary for 1.19.6.1 extracted from

Kavanagh, E.P.; Hill, S.
Oxygen inhibition of nitrogenase activity in Klebsiella pneumoniae (1992), J. Gen. Microbiol., 139, 1307-1314.

Search for more literature for 1.19.6.1

Inhibitors

Inhibitors	Comment	Organism	Structure
O2	complete reversible inhibition, reversibility decreases by increasing the time of exposure to O2	Klebsiella pneumoniae

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Mg2+	required for ATP hydrolysis	Klebsiella pneumoniae

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
6 reduced flavodoxin + N2 + 6 H2O + 6 ATP	Klebsiella pneumoniae	anaerobic conditions are required by the enzyme	6 oxidized flavodoxin + 2 NH3 + 6 H+ + 6 ADP + 6 phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Klebsiella pneumoniae	-	-	-

Oxidation Stability

Oxidation Stability	Organism
complete reversible inhibition by O2, reversibility decreases by increasing the time of exposure to O2, after 20 min 60% reversibility of the inhibition remains	Klebsiella pneumoniae

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
0.027	-	reductant dithionite	Klebsiella pneumoniae

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
6 reduced flavodoxin + N2 + 6 H2O + 6 ATP	-	Klebsiella pneumoniae	6 oxidized flavodoxin + 2 NH3 + 6 H+ + 6 ADP + 6 phosphate	-	?
6 reduced flavodoxin + N2 + 6 H2O + 6 ATP	anaerobic conditions are required by the enzyme	Klebsiella pneumoniae	6 oxidized flavodoxin + 2 NH3 + 6 H+ + 6 ADP + 6 phosphate	-	?
dithionite + H+ + N2 + ATP	-	Klebsiella pneumoniae	?	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)