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Literature summary for 1.2.1.104 extracted from

  • Hirabayashi, T.; Harada, T.
    Isolation and properties of a pyruvate dehydrogenase complex from the yeast Hansenula miso (1972), J. Biochem., 71, 797-804.
    View publication on PubMed
Search for more literature for 1.2.1.104

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
pyruvate + lipoamide Hansenula miso in overall reaction of pyruvate dehydrogenase complex, pyruvate can be replaced by 2-ketobutyrate S-acetyldihydrolipoamide + CO2
-
 ?
pyruvate + lipoamide Hansenula miso low reactivity with 2-ketovalerate S-acetyldihydrolipoamide + CO2
-
 ?
pyruvate + lipoamide Hansenula miso additional reactions of complex, e. g. reduction of K3Fe(CN)6 S-acetyldihydrolipoamide + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Hansenula miso
-
-
-

Purification (Commentary)

Purification (Comment) Organism
pyruvate dehydrogenase complex, composed of EC 1.2.4.1, EC 2.3.1.12, EC 1.8.1.4 Hansenula miso

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
pyruvate + lipoamide in overall reaction of pyruvate dehydrogenase complex, pyruvate can be replaced by 2-ketobutyrate Hansenula miso S-acetyldihydrolipoamide + CO2
-
 ?
pyruvate + lipoamide low reactivity with 2-ketovalerate Hansenula miso S-acetyldihydrolipoamide + CO2
-
 ?
pyruvate + lipoamide additional reactions of complex, e. g. reduction of K3Fe(CN)6 Hansenula miso S-acetyldihydrolipoamide + CO2
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
additional information
-
-
 Hansenula miso

Cofactor

Cofactor Comment Organism Structure
thiamine diphosphate
-
 Hansenula miso