Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Fluoropyruvate | acts as substrate analogue, competitive | Bos taurus | |
Pyruvamide | acts as substrate analogue, competitive | Bos taurus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.027 | - |
pyruvate | pH 7.6, 30°C, catalytic subunit E1 | Bos taurus | |
0.072 | - |
pyruvate | pH 7.6, 30°C, overall reaction of complex | Bos taurus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
pyruvate + CoA + NAD+ | - |
Bos taurus | acetyl-CoA + CO2 + NADH | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
thiamine diphosphate | Km value 0.0034 mM for overall reaction | Bos taurus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.02 | - |
Fluoropyruvate | pH 7.6, 30°C, overall reaction of complex | Bos taurus | |
0.02 | - |
Pyruvamide | pH 7.6, 30°C, overall reaction of complex | Bos taurus |