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Literature summary for 1.2.1.104 extracted from
- The acute effects of differential dietary fatty acids on human skeletal muscle pyruvate dehydrogenase activity (2008), J. Appl. Physiol., 104, 1-9.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | PDH activity can be downregulated by an increase in dietary fat, attenuated PHD contributes to the preferential oxidation of n-6 poly unsaturated fatty acids during moderate-intensity exercis | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| skeletal muscle | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| pyruvate + CoA + NAD+ | - |
Homo sapiens | acetyl-CoA + CO2 + NADH | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PDHa | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| thiamine diphosphate | - |
Homo sapiens | |
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Release 2023.1 (January 2023)
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