Application | Comment | Organism |
---|---|---|
medicine | the Plr-SDH-GAPDH complex participates in invasive streptococcal infections | Streptococcus pyogenes |
Cloned (Comment) | Organism |
---|---|
a 1008 bp DNA fragment from the plr-sdh-gapdh gene is ligated into the vector pGEX-6P-1 for expression of the protein in Escherichia coli BL212DE3 cells | Streptococcus pyogenes |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cell surface | in complex with the streptococcal plasmin receptor, Plr, and streptococcal surface dehydrogenase, SDH | Streptococcus pyogenes | 9986 | - |
extracellular | the Plr-SDH-GAPDH complex is expressed on the bacterial surface and released from cells | Streptococcus pyogenes | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptococcus pyogenes | P0C0G6 | - |
- |
Purification (Comment) | Organism |
---|---|
recombinant protein is purified using glutathione-Sepharose 4B and PreScission protease | Streptococcus pyogenes |
Synonyms | Comment | Organism |
---|---|---|
GAPDH | - |
Streptococcus pyogenes |
glyceraldehyde-3-phosphate dehydrogenase | - |
Streptococcus pyogenes |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
the enzymatic activity of cell-associated Plr-SDH-GAPDH complex is measured | Streptococcus pyogenes |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.5 | - |
the enzymatic activity of cell-associated Plr-SDH-GAPDH complex is measured | Streptococcus pyogenes |