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Literature summary for 1.2.1.12 extracted from

  • Wu, J.; Lin, F.; Qin, Z.
    Sequestration of glyceraldehyde-3-phosphate dehydrogenase to aggregates formed by mutant huntingtin (2007), Acta Biochim. Biophys. Sin. (Shanghai), 39, 885-890.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in MCF-7 cells Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information mutant htt shows co-localization of GAPDH with N-terminus of huntingtin aggregates Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Homo sapiens 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
36000
-
subunit, SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-glyceraldehyde 3-phosphate + phosphate + NAD+
-
Homo sapiens 3-phospho-D-glyceroyl phosphate + NADH + H+
-
?

Synonyms

Synonyms Comment Organism
D-glyceraldehyde-3-phosphate dehydrogenase
-
Homo sapiens
GAPDH
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Homo sapiens