Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-(dodec-1-en-1-yl)-6-hydroxybenzoic acid | inhibition is not reversed or prevented by addition of Triton X-100. Noncompetitive with respect to both substrate and cofactor | Trypanosoma cruzi | |
2-pentadecyl-6-hydroxybenzoic acid | inhibition is not reversed or prevented by addition of Triton X-100. Noncompetitive with respect to both substrate and cofactor | Trypanosoma cruzi |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma cruzi | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glyceraldehyde 3-phosphate + phosphate + NAD+ | - |
Trypanosoma cruzi | 3-phospho-D-glyceroyl phosphate + NADH | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Trypanosoma cruzi |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.002 | - |
2-pentadecyl-6-hydroxybenzoic acid | pH 8.9, 25°C, substrate D-glyceraldehyde 3-phosphate | Trypanosoma cruzi | |
0.004 | - |
2-(dodec-1-en-1-yl)-6-hydroxybenzoic acid | pH 8.9, 25°C, substrate D-glyceraldehyde 3-phosphate | Trypanosoma cruzi | |
0.004 | - |
2-pentadecyl-6-hydroxybenzoic acid | pH 8.9, 25°C, substrate NAD+ | Trypanosoma cruzi | |
0.005 | - |
2-(dodec-1-en-1-yl)-6-hydroxybenzoic acid | pH 8.9, 25°C, substrate NAD+ | Trypanosoma cruzi |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.028 | - |
pH 8.9, 25°C | Trypanosoma cruzi | 2-pentadecyl-6-hydroxybenzoic acid | |
0.055 | - |
pH 8.9, 25°C | Trypanosoma cruzi | 2-(dodec-1-en-1-yl)-6-hydroxybenzoic acid |