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Literature summary for 1.2.1.12 extracted from
- Carbon flux around leaf-cytosolic glyceraldehyde-3-phosphate dehydrogenase introduces a 13C signal in plant glucose (2021), J. Exp. Bot., 72, 7136-7144 .
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Pinus nigra | 5829 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-glyceraldehyde 3-phosphate + phosphate + NAD+ | Pinus nigra | - |
3-phospho-D-glyceroyl phosphate + NADH + H+ | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pinus nigra | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| leaf | - |
Pinus nigra | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-glyceraldehyde 3-phosphate + phosphate + NAD+ | - |
Pinus nigra | 3-phospho-D-glyceroyl phosphate + NADH + H+ | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| glyceraldehyde-3-phosphate dehydrogenase | - |
Pinus nigra |
| p-GAPDH | - |
Pinus nigra |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | - |
Pinus nigra | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | the enzyme is important in the carbon metabolism in plant leaves, overview | Pinus nigra |
| physiological function | a 13C signal (i.e. systematic 13C/12C variation) at tree-ring glucose C-4 signal seems to be introduced by glyceraldehyde-3-phosphate dehydrogenases in the cytosol of leaves, which means commitment of glyceraldehyde 3-phosphate to 3-phosphoglycerate versus fructose 1,6-bisphosphate metabolism, and the contribution of non-phosphorylating versus phosphorylating glyceraldehyde-3-phosphate dehydrogenase to catalysing the glyceraldehyde 3-phosphate to 3-phosphoglycerate forward reaction of glycolysis. Modelling of the cytosolic oxidation-reduction (COR) cycle, a carbon-neutral mechanism supplying NADPH at the expense of ATP and NADH, which may help to maintain leaf-cytosolic redox balances. Carbon isotope fractionation by glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is modelled. A positive correlation between air vapour pressure deficit and 13C discrimination at glucose C-4 is observed | Pinus nigra |
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Release 2023.1 (January 2023)
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