Literature summary for 1.2.1.24 extracted from

Choi, S.Y.; Bahn, J.H.; Lee, B.R.; Jeon, S.G.; Jang, J.S.; Kim, C.K.; Jin, L.H.; Kim, K.H.; Park, J.S.; Park, J.; Cho, S.W.
Brain succinic semialdehyde dehydrogenase: identification of reactive lysyl residues labeled with pyridoxal-5'-phosphate (2001), J. Neurochem., 76, 919-925.

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Inhibitors

Inhibitors	Comment	Organism	Structure
pyridoxal 5'-phosphate	catalytic function is modulated by binding of pyridoxal-5'-phosphate to specific Lys347 residue at or near the coenzyme-binding site of the protein, NAD+ protects from inactivation	Bos taurus

Organism

Organism	UniProt	Comment	Textmining
Bos taurus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Bos taurus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
succinate semialdehyde + NAD+ + H2O	-	Bos taurus	succinate + NADH	-	?

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	-	Bos taurus

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Release 2023.1 (January 2023)