Inhibitors | Comment | Organism | Structure |
---|---|---|---|
p-hydroxymercuribenzoate | - |
Mus musculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.03 | - |
4-hydroxy-2-nonenal | - |
Mus musculus | |
0.06 | - |
NAD+ | - |
Mus musculus | |
0.08 | - |
hexanal | - |
Mus musculus | |
0.11 | - |
benzaldehyde | - |
Mus musculus | |
0.12 | - |
trans-2-hexenal | - |
Mus musculus | |
1.4 | - |
NADP+ | - |
Mus musculus | |
15.63 | - |
acetaldehyde | - |
Mus musculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
59000 | - |
2 * 59000, SDS-PAGE | Mus musculus |
110000 | - |
gel filtration | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | dual role for the corneal enzyme in providing the eye with protection against UV-B light: by oxidizing aldehydes generated through light-induced lipid peroxidation and by direct absorption of UV-B light by the enzyme | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cornea | - |
Mus musculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
5.51 | - |
- |
Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-hydroxy-2-nonenal + NADP+ + H2O | - |
Mus musculus | 4-hydroxy-2-nonenoic acid + NADPH + H+ | - |
r | |
acetaldehyde + NAD+ + H2O | - |
Mus musculus | acetate + NADH + H+ | - |
? | |
benzaldehyde + NAD+ + H2O | - |
Mus musculus | benzoate + NADH + H+ | - |
? | |
benzaldehyde + NADP+ | - |
Mus musculus | benzoate + NADPH | - |
? | |
hexanal + NAD+ + H2O | - |
Mus musculus | hexanoate + NADH + H+ | - |
? | |
malondialdehyde + NAD+ | - |
Mus musculus | ? + NADH | - |
? | |
additional information | enzyme prefers aldehyde products of lipid peroxidation as substrates | Mus musculus | ? | - |
? | |
additional information | dual role for the corneal enzyme in providing the eye with protection against UV-B light: by oxidizing aldehydes generated through light-induced lipid peroxidation and by direct absorption of UV-B light by the enzyme | Mus musculus | ? | - |
? | |
trans-2-hexenal + NAD+ | - |
Mus musculus | trans-2-hexenoate + NADH | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 59000, SDS-PAGE | Mus musculus |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
18.8 | - |
NAD+ | reaction with benzyladehyde | Mus musculus | |
20.9 | - |
benzaldehyde | - |
Mus musculus | |
26.1 | - |
4-hydroxy-2-nonenal | - |
Mus musculus | |
33.1 | - |
NADP+ | reaction with benzaldehyde | Mus musculus | |
33.5 | - |
acetaldehyde | - |
Mus musculus | |
34 | - |
hexanal | - |
Mus musculus | |
35.1 | - |
trans-2-hexenal | - |
Mus musculus |