Application | Comment | Organism |
---|---|---|
additional information | ALDH2 may have antioxidant properties. Yeast ALDH significantly and dose-dependently attenuates HX/XO-generated O2S- signal | Saccharomyces cerevisiae |
additional information | reduced ALDH-2 activity and expression leads to decreased nitroglycerin bioconversion. ALDH is an important physiological inhibitory factor of superoxide production | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
benomyl | potent irreversible inhibitor of ALDH. Benomyl increases superoxide production as much as nitroglycerin | Rattus norvegicus | |
nitroglycerin | induces nitrate tolerance. Expression and activity of ALDH-2 is decreased in nitrate-tolerant rats | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | P11884 | male Wistar rats | - |
Saccharomyces cerevisiae | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
aorta | - |
Rattus norvegicus | - |
additional information | addition of ALDH to RASM cell homogenates significantly decreases NO consumption | Rattus norvegicus | - |
smooth muscle | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
benzaldehyde + NADP+ + H2O | - |
Saccharomyces cerevisiae | benzoate + NADPH + H+ | - |
? | |
benzaldehyde + NADP+ + H2O | - |
Rattus norvegicus | benzoate + NADPH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
aldehyde dehydrogenase 2 | - |
Saccharomyces cerevisiae |
aldehyde dehydrogenase 2 | - |
Rattus norvegicus |
ALDH2 | - |
Saccharomyces cerevisiae |
ALDH2 | - |
Rattus norvegicus |