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Literature summary for 1.2.1.5 extracted from

  • Tomita, H.; Tanaka, K.; Tanaka, T.; Hara, A.
    Aldehyde dehydrogenase 1A1 in stem cells and cancer (2016), Oncotarget, 7, 11018-11032.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.2.1.5

Application

Application Comment Organism
medicine high ALDH1 activity and ALDH1A1 overexpression are associated with poor cancer prognosis Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
adult stem cell
-
 Homo sapiens
-
cancer stem cell
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
ALDH1
-
 Homo sapiens
ALDH1A1 isotype Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Homo sapiens
NADP+
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function isotype ALDH1A1 is the key ALDH isozyme linked to tissue stem cells populations and an important contributor to cancer stem cells function in cancers Homo sapiens