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Literature summary for 1.2.1.68 extracted from
- A coniferyl aldehyde dehydrogenase gene from Pseudomonas sp. strain HR199 enhances the conversion of coniferyl aldehyde by Saccharomyces cerevisiae (2016), Biores. Technol., 212, 11-19 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| recombinant expression of the enzyme in Saccharomyces cerevisiae strain CEN.PK102-3A, deficient for acetaldehyde dehydrogenase Ald5 via deletion of ALD5, CALDH enzyme expression leads to increased coniferyl aldehyde conversion in the recombinant yeast strain. Effect of the conversion of coniferyl aldehyde on the lag phase of recombinant strains, overview | Pseudomonas sp. HR199 |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | improved endogenous conversion of phenolic compounds by heterologous expression of coniferyl aldehyde dehydrogenase enzyme from Pseudomonas in Saccharomyces cerevisiae, overview | Pseudomonas sp. HR199 |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| coniferaldehyde + CoA + NADP+ | Pseudomonas sp. HR199 | - |
feruloyl-CoA + NADPH + H+ | - |
? |  |
| coniferaldehyde + CoA + NADP+ | Pseudomonas sp. HR199 DSM 7063 | - |
feruloyl-CoA + NADPH + H+ | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pseudomonas sp. HR199 | Q86447 | - |
- |
| Pseudomonas sp. HR199 DSM 7063 | Q86447 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| additional information | the maximum specific growth rates of the strains in decreased by coniferaldehyde, no growth at 1.4 M coniferaldehyde | Pseudomonas sp. HR199 | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| coniferaldehyde + CoA + NADP+ | - |
Pseudomonas sp. HR199 | feruloyl-CoA + NADPH + H+ | - |
? | |
| coniferaldehyde + CoA + NADP+ | - |
Pseudomonas sp. HR199 DSM 7063 | feruloyl-CoA + NADPH + H+ | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| CALDH | - |
Pseudomonas sp. HR199 |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADP+ | - |
Pseudomonas sp. HR199 | |
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Release 2023.1 (January 2023)
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