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Literature summary for 1.2.1.70 extracted from

  • Richter, A.S.; Banse, C.; Grimm, B.
    The GluTR-binding protein is the heme-binding factor for feedback control of glutamyl-tRNA reductase (2019), eLife, 8, e46300 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.2.1.70

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21 cells Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
plastid
-
 Arabidopsis thaliana 9536
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-glutamate 1-semialdehyde + NADP+ + tRNAGlu Arabidopsis thaliana
-
 L-glutamyl-tRNAGlu + NADPH + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
 ecotype Col-0
-

Purification (Commentary)

Purification (Comment) Organism
Ni-NTA column chromatography and glutathione Sepharose column chromatography Arabidopsis thaliana

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-glutamate 1-semialdehyde + NADP+ + tRNAGlu
-
 Arabidopsis thaliana L-glutamyl-tRNAGlu + NADPH + H+
-
 ?
additional information binding of heme to the GluTR-binding protein (GBP) inhibits interaction of GBP with the N-terminal regulatory domain of isoform GluTR1, thus making it accessible to the Clp protease Arabidopsis thaliana ?
-
-

Synonyms

Synonyms Comment Organism
GluTR1 isoform Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
heme
-
 Arabidopsis thaliana