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Literature summary for 1.2.1.74 extracted from

  • Funk, C.; Croteau, R.
    Diterpenoid resin acid biosynthesis in conifers: characterization of two cytochrome P450-dependent monooxygenases and an aldehyde dehydrogenase involved in abietic acid biosynthesis (1994), Arch. Biochem. Biophys., 308, 258-266.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
additional information not inhibited by 90% CO Abies grandis

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
Abies grandis 5737
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
abietadienal + H2O + NAD+ Abies grandis last step of abietic acid biosynthesis. Abietic acid is the principle component of conifer resin as a defense secretion against insect and pathogen attack abietate + NADH + H+
-
?

Organism

Organism UniProt Comment Textmining
Abies grandis
-
Lindl.
-

Source Tissue

Source Tissue Comment Organism Textmining
stem cell-free stem extracts Abies grandis
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
abietadienal + H2O + NAD+
-
Abies grandis abietate + NADH + H+
-
?
abietadienal + H2O + NAD+ last step of abietic acid biosynthesis. Abietic acid is the principle component of conifer resin as a defense secretion against insect and pathogen attack Abies grandis abietate + NADH + H+
-
?

Synonyms

Synonyms Comment Organism
abieta-7-13-dien-18-al dehydrogenase
-
Abies grandis

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
32
-
assay at Abies grandis

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.6
-
assay at Abies grandis

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Abies grandis