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Literature summary for 1.2.1.75 extracted from

  • Zhou, S.; Lama, S.; Jiang, J.; Sankaranarayanan, M.; Park, S.
    Use of acetate for the production of 3-hydroxypropionic acid by metabolically-engineered Pseudomonas denitrificans (2020), Biores. Technol., 307, 123194 .
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Pseudomonas denitrificans strain ATCC 13867 Chloroflexus aurantiacus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
malonate semialdehyde + NADPH + H+ Chloroflexus aurantiacus
-
3-hydroxypropionic acid + NADP+
-
?
malonyl-CoA + NADPH + H+ Chloroflexus aurantiacus
-
malonate semialdehyde + CoA + NADP+
-
?

Organism

Organism UniProt Comment Textmining
Chloroflexus aurantiacus Q6QQP7
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
malonate semialdehyde + NADPH + H+
-
Chloroflexus aurantiacus 3-hydroxypropionic acid + NADP+
-
?
malonyl-CoA + NADPH + H+
-
Chloroflexus aurantiacus malonate semialdehyde + CoA + NADP+
-
?

Synonyms

Synonyms Comment Organism
malonyl-CoA reductase
-
Chloroflexus aurantiacus
MCR
-
Chloroflexus aurantiacus

Cofactor

Cofactor Comment Organism Structure
NADPH dependent on Chloroflexus aurantiacus