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Literature summary for 1.2.1.79 extracted from

  • Bartsch, K.; von Johnn-Marteville, A.; Schulz, A.
    Molecular analysis of two genes of the Escherichia coli gab cluster: nucleotide sequence of the glutamate:succinic semialdehyde transaminase gene (gabT) and characterization of the succinic semialdehyde dehydrogenase gene (gabD) (1990), J. Bacteriol., 172, 7035-7042.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
-
Escherichia coli

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
60000
-
x * 60000, calculated Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
succinate semialdehyde + NADP+ + H2O
-
Escherichia coli succinate + NADPH + 2 H+
-
?

Subunits

Subunits Comment Organism
? x * 60000, calculated Escherichia coli

Cofactor

Cofactor Comment Organism Structure
NADP+ enzyme is specific for NADP+ as a cofactor Escherichia coli

Expression

Organism Comment Expression
Escherichia coli the genes gabT, coding for glutamate:succinic semialdehyde transaminase, and gabD, encoding succinic semialdehyde dehydrogenase, are cotranscribed from a promoter located upstream of gabD additional information