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Literature summary for 1.2.1.8 extracted from

  • Rothschild, H.A.; Barron, E.S.
    The oxidation of betaine aldehyde be betaine aldehyde dehydrogenase (1954), J. Biol. Chem., 209, 511-523.
    View publication on PubMed
Search for more literature for 1.2.1.8

Activating Compound

Activating Compound Comment Organism Structure
Cys activates, optimal concentration: 1 mM Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
acetaldehyde
-
 Rattus norvegicus
DL-glyceraldehyde
-
 Rattus norvegicus
iodoacetamide
-
 Rattus norvegicus
iodoacetate
-
 Rattus norvegicus
Iodosobenzoate
-
 Rattus norvegicus
methyl(bis-beta-chloroethyl)amine
-
 Rattus norvegicus
PCMB
-
 Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.11
-
 Betaine aldehyde
-
 Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-
heart
-
 Rattus norvegicus
-
kidney
-
 Rattus norvegicus
-
liver
-
 Rattus norvegicus
-
small intestine
-
 Rattus norvegicus
-
spleen
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
betaine aldehyde + NAD+ + H2O
-
 Rattus norvegicus betaine + NADH
-
 ?
betaine aldehyde + NADP+ + H2O no activity with NAD+ Rattus norvegicus betaine + NADPH
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.8 9.2
-
 Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Rattus norvegicus