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Literature summary for 1.2.1.84 extracted from

  • Wang, Y.; Sun, Y.; You, Q.; Luo, W.; Wang, C.; Zhao, S.; Chai, G.; Li, T.; Shi, X.; Li, C.; Jetter, R.; Wang, Z.
    Three fatty acyl-coenzyme A reductases, BdFAR1, BdFAR2 and BdFAR3, are involved in cuticular wax primary alcohol biosynthesis in Brachypodium distachyon (2018), Plant Cell Physiol., 59, 527-543 .
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
expressed in Solanum lycopersicum, Arabidopsis thaliana and yeast Brachypodium distachyon
expressed in Solanum lycopersicum, Arabidopsis thaliana, and yeast Brachypodium distachyon

Organism

Organism UniProt Comment Textmining
Brachypodium distachyon
-
-
-
Brachypodium distachyon I1ISS8
-
-
Brachypodium distachyon I1IT05
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
 Brachypodium distachyon
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
docosanoyl-CoA + 2 NADPH + 2 H+
-
 Brachypodium distachyon 1-docosanol + CoA + 2 NADP+
-
 ?
docosanoyl-CoA + 2 NADPH + 2 H+ preferred substrate for isoform FAR1 Brachypodium distachyon 1-docosanol + CoA + 2 NADP+
-
 ?
hexacosanoyl-CoA + 2 NADPH + 2 H+
-
 Brachypodium distachyon 1-hexacosanol + CoA + 2 NADP+
-
 ?
hexacosanoyl-CoA + 2 NADPH + 2 H+ preferred substrate for isoform FAR2 Brachypodium distachyon 1-hexacosanol + CoA + 2 NADP+
-
 ?
hexacosanoyl-CoA + 2 NADPH + 2 H+ preferred substrate for isoform FAR3 Brachypodium distachyon 1-hexacosanol + CoA + 2 NADP+
-
 ?
tetracosanoyl-CoA + 2 NADPH + 2 H+
-
 Brachypodium distachyon 1-tetracosanol + CoA + 2 NADP+
-
 ?

Subunits

Subunits Comment Organism
? x * 58300, calculated from amino acid sequence Brachypodium distachyon
? x * 57300, calculated from amino acid sequence Brachypodium distachyon
? x * 55900, calculated from amino acid sequence Brachypodium distachyon

Synonyms

Synonyms Comment Organism
FAR1 isoform Brachypodium distachyon
FAR2 isoform Brachypodium distachyon
FAR3 isoform Brachypodium distachyon
fatty acyl-CoA reductase
-
 Brachypodium distachyon

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Brachypodium distachyon

Expression

Organism Comment Expression
Brachypodium distachyon expression of the enzyme gene is induced by drought, cold and abscisic acid treatments up

General Information

General Information Comment Organism
physiological function isoform FAR1 is involved in cuticular wax primary alcohol biosynthesis Brachypodium distachyon
physiological function isoform FAR2 is involved in cuticular wax primary alcohol biosynthesis Brachypodium distachyon
physiological function isoform FAR3 is involved in cuticular wax primary alcohol biosynthesis Brachypodium distachyon