Literature summary for 1.2.1.88 extracted from

Wu, G.; Bazer, F.W.; Davis, T.A.; Kim, S.W.; Li, P.; Marc Rhoads, J.; Carey Satterfield, M.; Smith, S.B.; Spencer, T.E.; Yin, Y.
Arginine metabolism and nutrition in growth, health and disease (2009), Amino Acids, 37, 153-168.

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Activating Compound

Activating Compound	Comment	Organism	Structure
N-acetylglutamate	-	Mammalia

Inhibitors

Inhibitors	Comment	Organism	Structure
ornithine	inhibits only the short enzyme form	Mammalia

Organism

Organism	UniProt	Comment	Textmining
Mammalia	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
additional information	other cell types express long-form	Mammalia	-
small intestine	short isoform	Mammalia	-

Synonyms

Synonyms	Comment	Organism
P5C synthase	-	Mammalia
pyrroline-5-carboxylate synthase	two isoforms: short form and long form	Mammalia

General Information

General Information	Comment	Organism
physiological function	one of three key regulatory enzyme of intestinal citrulline synthesis	Mammalia

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Release 2023.1 (January 2023)