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Literature summary for 1.2.1.92 extracted from

  • Yun, E.; Lee, S.; Kim, H.; Pelton, J.; Kim, S.; Ko, H.; Choi, I.; Kim, K.
    The novel catabolic pathway of 3,6-anhydro-L-galactose, the main component of red macroalgae, in a marine bacterium (2015), Environ. Microbiol., 17, 1677-1688.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Vibrio sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3,6-anhydro-alpha-L-galactopyranose + NAD(P)+ + H2O Vibrio sp. the enzyme is involved in a degradation pathway for 3,6-anhydro-alpha-L-galactose, a major component of the polysaccharides produced by red macroalgae, such as agarose and porphyran 3,6-anhydro-alpha-L-galactonate + NAD(P)H + H+
-
?

Organism

Organism UniProt Comment Textmining
Vibrio sp. H2IFE7
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Vibrio sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3,6-anhydro-alpha-L-galactopyranose + NAD(P)+ + H2O the enzyme is involved in a degradation pathway for 3,6-anhydro-alpha-L-galactose, a major component of the polysaccharides produced by red macroalgae, such as agarose and porphyran Vibrio sp. 3,6-anhydro-alpha-L-galactonate + NAD(P)H + H+
-
?
3,6-anhydro-alpha-L-galactopyranose + NAD(P)+ + H2O among the cofactors, NADP+, NAD+ and NADPH, the highest abundances of reaction products are observed when NADP+ is added to the crude enzyme reaction mixture Vibrio sp. 3,6-anhydro-alpha-L-galactonate + NAD(P)H + H+
-
?

Synonyms

Synonyms Comment Organism
AHG dehydrogenase
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Vibrio sp.
VejAHGD
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Vibrio sp.

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
assay at Vibrio sp.

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
assay at Vibrio sp.

Cofactor

Cofactor Comment Organism Structure
NAD+ among the cofactors, NADP+, NAD+ and NADPH, the highest abundances of reaction products are observed when NADP+ is added to the crude enzyme reaction mixture Vibrio sp.
NADP+ among the cofactors, NADP+, NAD+ and NADPH, the highest abundances of reaction products are observed when NADP+ is added to the crude enzyme reaction mixture Vibrio sp.

General Information

General Information Comment Organism
malfunction the enzyme is involved in a degradation pathway for 3,6-anhydro-alpha-L-galactose, a major component of the polysaccharides produced by red macroalgae, such as agarose and porphyran Vibrio sp.