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Literature summary for 1.2.3.1 extracted from

  • Vila, R.; Kurosaki, M.; Barzago, M.M.; Kolek, M.; Bastone, A.; Colombo, L.; Salmona, M.; Terao, M.; Garattini, E.
    Regulation and biochemistry of mouse molybdo-flavoenzymes. The DBA/2 mouse is selectively deficient in the expression of aldehyde oxidase homologues 1 and 2 and represents a unique source for the purification and characterization of aldehyde oxidase (2004), J. Biol. Chem., 279, 8668-8683.
    View publication on PubMed
Search for more literature for 1.2.3.1

Inhibitors

Inhibitors Comment Organism Structure
benzamidine 1 mM, 58% inhibition Mus musculus
menadione 0.005 mM, 74% inhibition; 0.005 mM, 87% inhibition Mus musculus
norharmane 0.02 mM, 87% inhibition Mus musculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.004
-
 benzaldehyde 25°C, pH 7.4 Mus musculus
0.008
-
 Butyraldehyde 25°C, pH 7.4 Mus musculus
0.012
-
 benzaldehyde 25°C, pH 7.4 Mus musculus
0.021
-
 Butyraldehyde 25°C, pH 7.4 Mus musculus
0.03
-
 retinalaldehyde 25°C, pH 7.4 Mus musculus
0.06
-
 2-hydroxypyrimidine 25°C, pH 7.4 Mus musculus
0.07
-
 retinalaldehyde 25°C, pH 7.4 Mus musculus
0.17
-
 2-hydroxypyrimidine 25°C, pH 7.4 Mus musculus
0.8
-
 acetaldehyde 25°C, pH 7.4 Mus musculus
0.82
-
 acetaldehyde 25°C, pH 7.4 Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-
Mus musculus
-
 CD-1 mouse
-
Mus musculus
-
 DBA/2 mouse
-
Mus musculus CD-1
-
 CD-1 mouse
-
Mus musculus DBA/2
-
 DBA/2 mouse
-

Purification (Commentary)

Purification (Comment) Organism
-
 Mus musculus
55°C, ammonium sulfate, Benzmidine-Sepharose, Mono Q Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
epidermis
-
 Mus musculus
-
liver
-
 Mus musculus
-
skin
-
 Mus musculus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.75
-
-
 Mus musculus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-hydroxypyrimidine + ferricyanide
-
 Mus musculus ?
-
 ?
2-hydroxypyrimidine + ferricyanide
-
 Mus musculus CD-1 ?
-
 ?
2-hydroxypyrimidine + ferricyanide
-
 Mus musculus DBA/2 ?
-
 ?
acetaldehyde + 2 ferricyanide + H2O
-
 Mus musculus acetate + 2 ferrocyanide + 2 H+
-
 ?
acetaldehyde + 2 ferricyanide + H2O
-
 Mus musculus CD-1 acetate + 2 ferrocyanide + 2 H+
-
 ?
acetaldehyde + 2 ferricyanide + H2O
-
 Mus musculus DBA/2 acetate + 2 ferrocyanide + 2 H+
-
 ?
benzaldehyde + 2 ferricyanide + H2O
-
 Mus musculus benzoate + 2 ferrocyanide + 2 H+
-
 ?
benzaldehyde + 2 ferricyanide + H2O
-
 Mus musculus CD-1 benzoate + 2 ferrocyanide + 2 H+
-
 ?
benzaldehyde + 2 ferricyanide + H2O
-
 Mus musculus DBA/2 benzoate + 2 ferrocyanide + 2 H+
-
 ?
benzaldehyde + O2 + H2O
-
 Mus musculus benzoate + H2O2
-
 ?
benzaldehyde + O2 + H2O
-
 Mus musculus CD-1 benzoate + H2O2
-
 ?
benzaldehyde + O2 + H2O
-
 Mus musculus DBA/2 benzoate + H2O2
-
 ?
butanal + 2 ferricyanide + H2O
-
 Mus musculus butanoate + 2 ferrocyanide + 2 H+
-
 ?
butanal + 2 ferricyanide + H2O
-
 Mus musculus CD-1 butanoate + 2 ferrocyanide + 2 H+
-
 ?
butanal + 2 ferricyanide + H2O
-
 Mus musculus DBA/2 butanoate + 2 ferrocyanide + 2 H+
-
 ?
phthalazine + ferricyanide
-
 Mus musculus 1-phthalazinone + ferrocyanide
-
 ?
phthalazine + ferricyanide
-
 Mus musculus ?
-
 ?
retinalaldehyde + O2 + H2O
-
 Mus musculus retinoic acid + H2O2
-
 ?

Synonyms

Synonyms Comment Organism
AHO2
-
 Mus musculus
AOH1
-
 Mus musculus
AOX1
-
 Mus musculus

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.0007
-
 norharmane 25°C, pH 7.4 Mus musculus