Application | Comment | Organism |
---|---|---|
additional information | NMR techniques to determine the structure of hbSBD and dynamics of several truncated constructs from the E2 component, including hbLBD (residues 184), hbSBD (residues 111149), and a di-domain (hbDD) (residues 1166) comprising hbLBD, hbSBD and the interdomain linker, the presence of the interdomain linker restricts the motional freedom of the hbSBD more significantly than hbLBD, the linker region likely exists as a soft rod rather than a flexible string in solution | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
by Ni-NTA affinity chromatography | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
BCKDC | - |
Homo sapiens |
branched chain alpha-ketoacid dehydrogenase complex | - |
Homo sapiens |
E2 | - |
Homo sapiens |
More | - |
Homo sapiens |
More | scaffold of the human branched-chain alpha-ketoacid dehydrogenase complex, contains the lipoyl-bearing domain (hbLBD), the subunit-binding domain (hbSBD) and the inner core domain that are linked to carry out E2 functions in substrate channeling and recognition | Homo sapiens |