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Literature summary for 1.2.7.4 extracted from

  • Möller-Zinkhan, D.; Thauer, R.K.
    Anaerobic lactate oxidation to 3 CO2 by Archaeoglobus fulgidus via the carbon monoxide dehydrogenase pathway: demonstration of the acetyl-CoA carbon-carbon cleavage reaction in cell extract (1990), Arch. Microbiol., 153, 215-218.
No PubMed abstract available

General Stability

General Stability Organism
CN- inactivates Archaeoglobus fulgidus

Inhibitors

Inhibitors Comment Organism Structure
CN-
-
Archaeoglobus fulgidus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.35
-
CO
-
Archaeoglobus fulgidus
1.4
-
methyl viologen
-
Archaeoglobus fulgidus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
CO + H2O + electron acceptor Archaeoglobus fulgidus key enzyme in C1-pathway of acetyl-CoA degradation ?
-
?

Organism

Organism UniProt Comment Textmining
Archaeoglobus fulgidus
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.001 0.002 CO2/acetyl-CoA exchange in cell extracts at 85°C Archaeoglobus fulgidus
5.7
-
CO oxidation in cell-extracts at 85°C, electron acceptor methylviologen Archaeoglobus fulgidus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CO + H2O + electron acceptor key enzyme in C1-pathway of acetyl-CoA degradation Archaeoglobus fulgidus ?
-
?
CO + H2O + methyl viologen catalyzes an exchange reaction between CO and the carbonyl group of acetyl-CoA Archaeoglobus fulgidus CO2 + reduced methyl viologen
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7 9
-
Archaeoglobus fulgidus