Literature summary for 1.2.7.6 extracted from

Straub, C.T.; Schut, G.; Otten, J.K.; Keller, L.M.; Adams, M.W.W.; Kelly, R.M.
Modification of the glycolytic pathway in Pyrococcus furiosus and the implications for metabolic engineering (2020), Extremophiles, 24, 511-518 .

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Organism

Organism	UniProt	Comment	Textmining
Pyrococcus furiosus	Q8U3K2	-	-

Synonyms

Synonyms	Comment	Organism
GAPOR	-	Pyrococcus furiosus
Gor	-	Pyrococcus furiosus

General Information

General Information	Comment	Organism
physiological function	either of the two enzymes, ferredoxin-dependent glyceraldehyde-3-phosphate ferredoxin oxidoreductase (GAPOR) or NADP+-dependent non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN), involved in the modified Embden-Meyerhof glycolytic pathway can be deleted individually without impacting viability, albeit with differences in native fermentation product profiles. Pyrococcus furiosus is viable in the gluconeogenic direction (growth on pyruvate or peptides plus elemental sulfur) in a DAPOR/GAPN double deletion strain.	Pyrococcus furiosus

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Release 2023.1 (January 2023)