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Literature summary for 1.3.1.119 extracted from

  • Raschke, H.; Fleischmann, T.; Van Der Meer, J.R.; Kohler, H.P.
    cis-chlorobenzene dihydrodiol dehydrogenase (TcbB) from Pseudomonas sp. strain P51, expressed in Escherichia coli DH5alpha(pTCB149), catalyzes enantioselective dehydrogenase reactions (1999), Appl. Environ. Microbiol., 65, 5242-5246 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli DH5a(pTCB149) Pseudomonas sp. P51

Organism

Organism UniProt Comment Textmining
Pseudomonas sp. P51 Q52387
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(+)-cis-2',3'-dihydroxy-2',3'-dihydro-2-chlorobiphenyl + NAD+
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Pseudomonas sp. P51 2,3-dihydroxy-2'-chlorobiphenyl + NADH + H+
-
?
(+)-cis-2',3'-dihydroxy-2',3'-dihydro-3-chlorobiphenyl + NAD+
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Pseudomonas sp. P51 2,3-dihydroxy-3'-chlorobiphenyl + NADH + H+
-
?
(+)-cis-2',3'-dihydroxy-2',3'-dihydro-4-chlorobiphenyl + NAD+
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Pseudomonas sp. P51 2,3-dihydroxy-4'-chlorobiphenyl + NADH + H+
-
?
(1S)-1-indanol + NAD+ with racemic 1-indanol, the enzyme enantioselectively transforms the (1S) enantiomer to 1-indanone Pseudomonas sp. P51 1-indanone + NADH + H+
-
?
cis-(1R,2S)-1,2-dihydroxy-1,2,3,4-tetrahydronaphthalene + NAD+ the enzyme oxidizes both enantiomers of cis-1,2-dihydroxy-1,2,3,4-tetrahydronaphthalene, but oxidation of the cis-(1S,2R) enantiomer is delayed until the cis-(1R,2S) enantiomer is completely depleted Pseudomonas sp. P51 1,2-dihydroxy-3,4-dihydronaphthalene + NADH + H+
-
?
cis-(1R,2S)-1,2-indandiol + NAD+ no activity with the cis-(1S,2R) enantiomer Pseudomonas sp. P51 1,2-indenediol + NADH + H+
-
?
cis-(1S,2R)-1,2-dihydroxy-1,2,3,4-tetrahydronaphthalene + NAD+ the enzyme oxidizes both enantiomers of cis-1,2-dihydroxy-1,2,3,4-tetrahydronaphthalene, but oxidation of the cis-(1S,2R) enantiomer is delayed until the cis-(1R,2S) enantiomer is completely depleted Pseudomonas sp. P51 1,2-dihydroxy-3,4-dihydronaphthalene + NADH + H+
-
?
cis-toluene dihydrodiol + NAD+
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Pseudomonas sp. P51 3-methylcatechol + NADH + H+
-
?
additional information the enzyme also acts as an alcohol dehydrogenase Pseudomonas sp. P51 ?
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?

Synonyms

Synonyms Comment Organism
CDD
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Pseudomonas sp. P51
cis-chlorobenzene dihydrodiol dehydrogenase
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Pseudomonas sp. P51
TcbB
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Pseudomonas sp. P51