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Literature summary for 1.3.1.13 extracted from

  • Gamborg, O.L.; Keeley, F.W.
    Aromatic metabolism in plants I. A study of the prephenate dehydrogenase from bean plants (1966), Biochim. Biophys. Acta, 115, 65-72.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
4-chloromercuriphenylsulfonic acid
-
Phaseolus vulgaris
N-ethylmaleimide
-
Phaseolus vulgaris

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.077
-
NADP+
-
Phaseolus vulgaris
0.079
-
NADP+
-
Phaseolus vulgaris
0.13
-
prephenate
-
Phaseolus vulgaris
0.18
-
prephenate
-
Phaseolus vulgaris

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
prephenate + NADP+ Phaseolus vulgaris
-
4-hydroxyphenylpyruvate + CO2 + NADPH
-
?
prephenate + NADP+ Vicia faba
-
4-hydroxyphenylpyruvate + CO2 + NADPH
-
?
prephenate + NADP+ Klebsiella aerogenes
-
4-hydroxyphenylpyruvate + CO2 + NADPH
-
?
prephenate + NADP+ Vigna radiata
-
4-hydroxyphenylpyruvate + CO2 + NADPH
-
?
prephenate + NADP+ Phaseolus coccineus
-
4-hydroxyphenylpyruvate + CO2 + NADPH
-
?

Organism

Organism UniProt Comment Textmining
Klebsiella aerogenes
-
-
-
no activity in Beta vulgaris subsp. vulgaris
-
red beet, Beta vulgaris ssp. var. conditiva, Beta vulgaris ssp. vulgaris var. rubra
-
no activity in Oryza sativa
-
rice
-
no activity in Pisum sativum
-
pea
-
no activity in Triticum aestivum
-
wheat
-
Phaseolus coccineus
-
scarlet runner bean, L.
-
Phaseolus vulgaris
-
wax bean, L. var.Bountiful
-
Vicia faba
-
broad bean, L. var. Windsor
-
Vigna radiata
-
mung bean, [L.] Wilczek, originally classified as Phaseolus aureus [L.] Roxb.
-

Purification (Commentary)

Purification (Comment) Organism
-
Phaseolus vulgaris

Source Tissue

Source Tissue Comment Organism Textmining
cotyledon
-
Phaseolus vulgaris
-
cotyledon
-
Vicia faba
-
cotyledon
-
Vigna radiata
-
cotyledon
-
Phaseolus coccineus
-
seedling
-
Vigna radiata
-
shoot
-
Vigna radiata
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
prephenate + NADP+
-
Phaseolus vulgaris 4-hydroxyphenylpyruvate + CO2 + NADPH
-
?
prephenate + NADP+
-
Vicia faba 4-hydroxyphenylpyruvate + CO2 + NADPH
-
?
prephenate + NADP+
-
Klebsiella aerogenes 4-hydroxyphenylpyruvate + CO2 + NADPH
-
?
prephenate + NADP+
-
Vigna radiata 4-hydroxyphenylpyruvate + CO2 + NADPH
-
?
prephenate + NADP+
-
Phaseolus coccineus 4-hydroxyphenylpyruvate + CO2 + NADPH
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
-
Phaseolus vulgaris
7.5
-
-
Vigna radiata

pH Range

pH Minimum pH Maximum Comment Organism
4 10.8
-
Phaseolus vulgaris

pH Stability

pH Stability pH Stability Maximum Comment Organism
7 8 maximum stability in this range at 22Ā°C Phaseolus vulgaris

Cofactor

Cofactor Comment Organism Structure
NADP+ NAD+ is ineffective in replacing NADP+ Phaseolus vulgaris