Application | Comment | Organism |
---|---|---|
medicine | resistance to doxorubicin and cisplatin in lung adenocarcinoma cell lines is closely associated with enzyme isoforms DDH1 and DDH2 activity | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
additional information | overexpression of enzyme in lung adenocarcinoma cell lines results in a much higher resistance to doxorubicin, cisplatin and irradiation. Isoforms DDH2 and DDH1 transfectants show higher drug and radiation resistance than DDH3 transfectants | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
NCI-H1437 cell | lung adenocarcinoma cell line | Homo sapiens | - |
NCI-H1684 cell | lung adenocarcinoma cell line | Homo sapiens | - |
NCI-H2009 cell | lung adenocarcinoma cell line | Homo sapiens | - |
NCI-H2087 cell | lung adenocarcinoma cell line | Homo sapiens | - |
NCI-H2126 cell | lung adenocarcinoma cell line | Homo sapiens | - |
NCI-H23 cell | lung adenocarcinoma cell line | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
DDH1 | - |
Homo sapiens |
DDH2 | - |
Homo sapiens |