Literature summary for 1.3.1.22 extracted from

Kaefer, M.; Audia, J.E.; Bruchovsky, N.; Goode, R.L.; Hsiao, K.C.; Leibovitch, I.Y.; Krushinski, J.H.; Lee, C; Steidle, C.P.; et al.
Charaterization of type I 5alpha-reductase activity in DU145 human prostatic adenocarcinoma cells (1996), J. Steroid Biochem. Mol. Biol., 58, 195-205.

Search for more literature for 1.3.1.22

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
prostate gland	studies in DU 145 cells, a human cell-line of low androgen sensitivity derived from a cerebral metastasis of an ephithelial prostate cancer	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
testosterone + NADPH + H+	-	Homo sapiens	17beta-hydroxy-5alpha-androstan-3-one + NADP+	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)