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Literature summary for 1.3.1.22 extracted from

  • Pratis, K.; O'Donnell, L.; Ooi, G.T.; Stanton, P.G.; McLachlan, R.I.; Robertson, D.M.
    Differential regulation of rat testicular 5alpha-reductase type 1 and 2 isoforms by testosterone and FSH (2003), J. Endocrinol., 176, 393-403.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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treatment with testosterone and estradiol
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Source Tissue

Source Tissue Comment Organism Textmining
testis decrease in isoenzyme 1 activity and mRNA during testosterone treatment, but not isoenzyme 2. Active immunisation of animals against gonadotrophin-releasing hormone, increase in activity of both isoenzymes Rattus norvegicus
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