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Literature summary for 1.3.1.24 extracted from

  • Liu, Y.; Liu, J.; Tetzlaff, W.; Paty, D.W.; Cynader, M.S.
    Biliverdin reductase, a major physiologic cytoprotectant, suppresses experimental autoimmune encephalomyelitis (2006), Free Radic. Biol. Med., 40, 960-967.
    View publication on PubMed
Search for more literature for 1.3.1.24

Application

Application Comment Organism
medicine BVR may represent a novel strategy for the treatment of multiple sclerosis and other oxidative stress-mediated diseases, treatment with BVR ameliorates both clinical and pathological signs of autoimmune encephalomyelitis more efficiently than treatments with traditional antioxidant enzymes Rattus norvegicus

Cloned(Commentary)

Cloned (Comment) Organism
expression in SH-SY5Y cells Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
astrocyte
-
 Rattus norvegicus
-
macrophage
-
 Rattus norvegicus
-
neuron
-
 Rattus norvegicus
-
spinal cord inflamed lesions, increased in rats with clinical autoimmune encephalomyelitis, also present in both white and gray matter Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
biliverdin + NAD(P)H + H+
-
 Rattus norvegicus bilirubin + NAD(P)+
-
 ?

Synonyms

Synonyms Comment Organism
BVR
-
 Rattus norvegicus