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BRENDA support

Literature summary for 1.3.1.24 extracted from

  • Barone, E.; Mancuso, C.; Di Domenico, F.; Sultana, R.; Murphy, M.P.; Head, E.; Butterfield, D.A.
    Biliverdin reductase-A: a novel drug target for atorvastatin in a dog pre-clinical model of Alzheimer disease (2012), J. Neurochem., 120, 135-146.
    View publication on PubMed
Search for more literature for 1.3.1.24

Organism

Organism UniProt Comment Textmining
Canis lupus familiaris
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
phosphoprotein atorvastatin significantly increases tyrosine phosphorylation Canis lupus familiaris

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Canis lupus familiaris
-
cerebellum
-
 Canis lupus familiaris
-
cerebral cortex
-
 Canis lupus familiaris
-
liver
-
 Canis lupus familiaris
-

Synonyms

Synonyms Comment Organism
Biliverdin reductase-A
-
 Canis lupus familiaris
BVR-A
-
 Canis lupus familiaris

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Canis lupus familiaris

Expression

Organism Comment Expression
Canis lupus familiaris atorvastatin significantly increases BVR-A protein levels, phosphorylation and activity only in parietal cortex up

General Information

General Information Comment Organism
physiological function BVR-A up-regulation and post-translational modifications significantly correlate with beta-secretase protein levels in the brain Canis lupus familiaris