Literature summary for 1.3.1.6 extracted from

Shiomi, K.; Hatano, H.; Morimoto, H.; Ui, H.; Sakamoto, K.; Kita, K.; Tomoda, H.; Lee, E.W.; Heo, T.R.; Kawagishi, H.; Omura, S.
Decursin and decursinol angelate selectively inhibit NADH-fumarate reductase of Ascaris suum (2007), Planta Med., 73, 1478-1481.

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Inhibitors

Inhibitors	Comment	Organism	Structure
decursin	-	Ascaris suum
decursinol	-	Ascaris suum
decursinol angelate	-	Ascaris suum

Organism

Organism	UniProt	Comment	Textmining
Ascaris suum	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
fumarate + NADH + H+	-	Ascaris suum	succinate + NAD+	-	?

Synonyms

Synonyms	Comment	Organism
NADH-fumarate reductase	-	Ascaris suum
NFRD	-	Ascaris suum

Cofactor

Cofactor	Comment	Organism	Structure
NADH	-	Ascaris suum

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.0011	-	-	Ascaris suum	decursin
0.0027	-	-	Ascaris suum	decursinol angelate
0.0048	-	-	Ascaris suum	decursinol

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Release 2023.1 (January 2023)